sciencebriefs
13:00in productionCh. 1 · Eyes moving behind closed lids/ 13:00 · ceiling 15 min
Neuroscience · Medicine

Rapid eye movement sleep

Kleitman and Aserinsky's 1953 discovery gave dream research a measurable brain state, rapid eye movement sleep, but seven decades on, what REM sleep actually evolved to do remains a genuinely open question.

In 1953 Nathaniel Kleitman and his student Eugene Aserinsky identified rapid eye movement sleep, a phase marked by waking-like brain activity, near-total muscle paralysis and vivid dreaming, verified by repeating the observation on Kleitman's own daughter before publishing. The finding, later extended by researchers including William Dement and Michel Jouvet, established a durable physiological description of a sleep stage occupying about a fifth to a quarter of adult sleep, arriving in repeated cycles through the night. Competing theories about REM sleep's function, memory consolidation, brain development, thermoregulation, remain unresolved, and the discovery's clinical legacy includes REM sleep behaviour disorder, a condition where the usual muscle paralysis fails and sleepers physically act out their dreams.

Chapters & takeaways6
  1. 0:08
    Eyes moving behind closed lids

    Kleitman and Aserinsky's 1953 discovery identified a sleep phase with rapid eye movement, waking-like brain activity and near-total muscle paralysis, linked to vivid dreaming.

  2. 2:10
    Verified on the discoverer's own daughter

    Kleitman had the finding repeated on his daughter before publishing, an early instance of insisting on independent verification.

  3. 4:20
    A measurable stage in a ninety-minute cycle

    REM sleep occupies roughly twenty to twenty-five per cent of adult sleep, recurring in lengthening periods across a night's roughly ninety-minute sleep cycles.

  4. 6:30
    A durable physiological description

    The brain activity, muscle atonia and neurochemical shifts that define REM sleep have held up and remain the standard basis for sleep lab measurement today.

  5. 8:40
    Competing theories, no clear winner

    Memory consolidation, brain development and other functions all remain candidate explanations for REM sleep, without settled consensus.

  6. 10:50
    When the paralysis fails

    REM sleep behaviour disorder, in which muscle atonia doesn't develop properly, lets sleepers physically act out dreams, distinct from sleepwalking.

Worth your time?

Yes. Study the whole thing.

4/ 5
What works
  • keeps the well-established physiological description distinct from the unresolved functional theories
  • highlights the verification step, testing the finding on Kleitman's own daughter, as a real detail about scientific caution
  • connects the 1953 discovery directly to a modern clinical condition
What does not
  • cannot say definitively why REM sleep evolved
  • does not resolve the conflicting evidence on whether REM deprivation actually impairs memory
Study it if
  • anyone curious what actually happens physiologically when we dream
  • readers interested in how a single careful observation founded a scientific field
  • people wanting an honest account of what remains unknown about sleep
Skip it if
  • readers wanting a definitive answer to what dreams or REM sleep are for
  • anyone expecting the memory-consolidation theory to be presented as settled fact
The written brief4 min read

Eyes moving behind closed lids

In 1953, Nathaniel Kleitman and his graduate student Eugene Aserinsky identified a distinct phase of sleep marked by rapid, darting eye movements beneath closed eyelids, brain activity that looked more like wakefulness than deep sleep, and near-total paralysis of the body’s voluntary muscles. Aserinsky first noticed the pattern while using an early electroencephalogram machine that produced roughly half a mile of paper output each night; Kleitman, wanting the finding checked independently, had the experiment repeated on his own daughter before the pair felt confident enough to publish. Their central claim was that this phase, rapid eye movement or REM sleep, was closely associated with vivid dreaming and was physiologically distinct from the quieter, slow-wave sleep that surrounds it, giving dream research for the first time a measurable, objective marker rather than relying solely on what someone remembered on waking.

Verified on the discoverer’s own daughter

Identifying REM sleep required treating sleep itself as something that could be continuously measured rather than simply observed. Kleitman and Aserinsky recorded eye movements alongside brain electrical activity through the night, then correlated the physiological pattern with reports from sleepers woken during it, who described dreaming far more often and more vividly than those woken during other sleep stages. The finding held up once other researchers, including William Dement and Michel Jouvet, extended the initial observation and mapped it onto the fuller architecture of a night’s sleep: REM sleep occupies roughly twenty to twenty-five per cent of adult sleep time, arriving in several distinct periods across the night, each one typically longer than the last, embedded within a cycle of alternating sleep stages that repeats roughly every ninety minutes.

A measurable stage in a ninety-minute cycle

The physiological picture established in 1953 and refined afterward has proven remarkably durable: during REM sleep, the brain’s electrical activity closely resembles a waking state even though the body’s motor neurons are actively suppressed, a genuine paralysis that prevents the sleeper from physically acting out what is being dreamed. This muscle atonia and the accompanying brain activity pattern have since been traced to specific neurochemical changes, including a shift toward high acetylcholine and a near-absence of certain other neurotransmitters during REM compared with waking or non-REM sleep. William Dement, another of Kleitman’s students, later described 1953 as the year sleep research became a genuine scientific field, and the basic measurement approach Kleitman and Aserinsky pioneered, tracking eye movement and brain activity together through the night, remains the standard method sleep laboratories use today.

A durable physiological description

What remains unsettled, seven decades on, is exactly what REM sleep is for. Several theories compete without a clear winner: that it consolidates certain kinds of memory, particularly procedural and emotional memory, since REM sleep measurably increases after intensive learning in some studies; that it supports early brain development, given that newborns spend over eighty per cent of their sleep in an REM-like state that declines sharply through childhood; and that it serves other functions entirely, including thermoregulation or immune support. Complicating the memory theory specifically, some research has found that people deprived of REM sleep do not show the memory impairment the theory would predict, which is why researchers describe these explanations as competing hypotheses rather than an established consensus.

Competing theories, no clear winner

The discovery mattered beyond the sleep laboratory because it gave clinical medicine a specific, measurable failure mode to look for when the underlying mechanism breaks down. REM sleep behaviour disorder occurs when the muscle paralysis that normally accompanies REM sleep fails to develop properly, leaving people to physically act out their dreams, a condition clearly distinguished from sleepwalking, which happens during a different, non-REM stage of sleep entirely. Recognising REM as a distinct physiological state also reshaped how researchers study sleep-related conditions generally, since a treatment or diagnosis can now be pinned to a specific, objectively measurable stage of the sleep cycle rather than to a vague category of disturbed rest, a precision that would not have been possible before 1953.

When the paralysis fails

This is worth the time as an example of how a genuinely new scientific field can begin with a single careful observation and a healthy dose of scepticism, since Kleitman’s insistence on repeating the finding on his own daughter before publishing is itself a small, instructive detail about how discoveries get verified rather than simply announced. The material rewards attention to what has and has not been settled: the physiological description of REM sleep, its brain activity, its muscle paralysis, its place in the sleep cycle, is now solid and well replicated, while the deeper question of why REM sleep evolved at all remains genuinely open across several competing theories. Readers wanting a definitive answer to what dreams are for will not get one here, but the honest uncertainty is itself part of what makes this worth reading closely.

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